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One year after completing treatment with PAPZIMEOS in a clinical study, 51% of patients (18 of 35) remained surgery free.
You may be able to
THROW OUT THE
BROKEN RECORD
OF RRP SURGERIES

PAPZIMEOS is the first FDA-approved medication that targets the root cause of recurrent respiratory papillomatosis (RRP) in adults.

Before your first dose, your doctor will remove any papillomas they can see. You may need another surgery before your third and/or fourth doses.

Hear from patients and doctors
A cropped circle shows a man throwing broken record of RRP surgery out of a window.
1 year after completing treatment with PAPZIMEOS in a clinical study,
51% of people (18 of 35)
remained surgery free
See how long PAPZIMEOS worked
Before your first dose, your doctor will remove any papillomas they can see. You may need another surgery before your third and/or fourth doses.

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You’re 4 doses
away from a
chance at
more surgery-free time with PAPZIMEOS

What is PAPZIMEOS?

PAPZIMEOS is a type of immunotherapy used to treat a condition called recurrent respiratory papillomatosis (RRP) in adults.

Important Safety Information

What is the most important information I should know about PAPZIMEOS?

Some people may have a reaction to the shot. Signs and symptoms may include redness, pain, swelling, itching, or warmth where the shot was given. After your first treatment, your healthcare provider will watch you for at least 30 minutes to make sure you're feeling okay.

Please contact your doctor immediately if you develop an infection, the reaction to your shot worsens, or you experience any of the below symptoms, which may indicate a systemic allergic reaction:

  • Difficulty breathing
  • Widespread rash
  • Facial swelling

Thrombotic events (blood clots that block your blood vessels) may occur after your PAPZIMEOS shot. Please notify your doctor immediately if you have the following symptoms:

  • Shortness of breath
  • Chest pain
  • Leg swelling
  • Persistent abdominal pain
  • Severe or persistent headaches
  • Blurred vision

What should I know before taking PAPZIMEOS?

Before taking PAPZIMEOS, tell your healthcare provider about all of your medical conditions, including:

  • If you are pregnant or plan to become pregnant because it is not known if PAPZIMEOS will harm the unborn baby.
  • If you are breastfeeding or plan to breastfeed. It is unknown if PAPZIMEOS is present in breast milk, or how it affects the breastfeeding child or milk production. Talk to your healthcare provider about the best way to feed your baby during treatment with PAPZIMEOS.

What are the most common side effects of PAPZIMEOS?

The most common side effects include:

  • Pain, redness, or swelling where the shot was given
  • Feeling tired
  • Chills
  • Fever
  • Muscle aches
  • Nausea (feeling sick)
  • Headache
  • Increased heart rate
  • Diarrhea
  • Vomiting
  • Sweating a lot

These are not all of the possible side effects of PAPZIMEOS. Call your healthcare provider for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088. You may also report side effects to Precigen, Inc. at 1-855-PGE-NRRP (1-855-743-6777).

Please see full Prescribing Information.

What is PAPZIMEOS?

PAPZIMEOS is a type of immunotherapy used to treat a condition called recurrent respiratory papillomatosis (RRP) in adults.

Important Safety Information

What is the most important information I should know about PAPZIMEOS?

Some people may have a reaction to the shot. Signs and symptoms may include redness, pain, swelling, itching, or warmth where the shot was given. After your first treatment, your healthcare provider will watch you for at least 30 minutes to make sure you're feeling okay.

What is PAPZIMEOS?

PAPZIMEOS is a type of immunotherapy used to treat a condition called recurrent respiratory papillomatosis (RRP) in adults.

Important Safety Information

What is the most important information I should know about PAPZIMEOS?

Some people may have a reaction to the shot. Signs and symptoms may include redness, pain, swelling, itching, or warmth where the shot was given. After your first treatment, your healthcare provider will watch you for at least 30 minutes to make sure you're feeling okay.

Please contact your doctor immediately if you develop an infection, the reaction to your shot worsens, or you experience any of the below symptoms, which may indicate a systemic allergic reaction:

  • Difficulty breathing
  • Widespread rash
  • Facial swelling

Thrombotic events (blood clots that block your blood vessels) may occur after your PAPZIMEOS shot. Please notify your doctor immediately if you have the following symptoms:

  • Shortness of breath
  • Chest pain
  • Leg swelling
  • Persistent abdominal pain
  • Severe or persistent headaches
  • Blurred vision

What should I know before taking PAPZIMEOS?

Before taking PAPZIMEOS, tell your healthcare provider about all of your medical conditions, including:

  • If you are pregnant or plan to become pregnant because it is not known if PAPZIMEOS will harm the unborn baby.
  • If you are breastfeeding or plan to breastfeed. It is unknown if PAPZIMEOS is present in breast milk, or how it affects the breastfeeding child or milk production. Talk to your healthcare provider about the best way to feed your baby during treatment with PAPZIMEOS.

What are the most common side effects of PAPZIMEOS?

The most common side effects include:

  • Pain, redness, or swelling where the shot was given
  • Feeling tired
  • Chills
  • Fever
  • Muscle aches
  • Nausea (feeling sick)
  • Headache
  • Increased heart rate
  • Diarrhea
  • Vomiting
  • Sweating a lot

These are not all of the possible side effects of PAPZIMEOS. Call your healthcare provider for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088. You may also report side effects to Precigen, Inc. at 1-855-PGE-NRRP (1-855-743-6777).

Please see full Prescribing Information.

HPV=human papillomavirus; RRP=recurrent respiratory papillomatosis.