Starting PAPZIMEOS?
Make PAPZIMEOS your first choice
to treat your recurrent respiratory papillomatosis (RRP)
PAPZIMEOS is the first and only FDA-approved immunotherapy used to treat adults with RRP
PAPZIMEOS trains your immune system to find and destroy papilloma cells infected with HPV (human papillomavirus) 6 or HPV 11.
PAPZIMEOS is a single course of treatment that may lead to fewer surgeries*
PAPZIMEOS is injected just under the skin (a subcutaneous injection) and can only be given by a healthcare professional.
Because PAPZIMEOS is a specialty medicine, your ENT (ear, nose, and throat) specialist may need to work with other specialists and facilities that can help store and give PAPZIMEOS.
*Before your first dose, you will need to have a procedure to remove any visible papillomas. Your doctor may consider an additional procedure to remove any visible papillomas before the third or fourth doses.
PAPZIMEOS will be sent to a healthcare provider’s office,
where you will go to receive the 4 injections over 12 weeks.*
*Before your first dose, you will need to have a procedure to remove any visible papillomas. Your doctor may consider an additional procedure to remove any visible papillomas before the third or fourth doses. Please ask your doctor if you have any questions about treatment.
- The second dose should be given no less than 11 days after the first dose
- After your first treatment, your healthcare provider will watch you for at least 30 minutes to make sure you're feeling okay
Some people may have a reaction to the shot. Signs and symptoms may include redness, pain, swelling, itching, or warmth where the shot was given.
What is PAPZIMEOS?
PAPZIMEOS is a type of immunotherapy used to treat a condition called recurrent respiratory papillomatosis (RRP) in adults.
Important Safety Information
What is the most important information I should know about PAPZIMEOS?
Some people may have a reaction to the shot. Signs and symptoms may include redness, pain, swelling, itching, or warmth where the shot was given. After your first treatment, your healthcare provider will watch you for at least 30 minutes to make sure you're feeling okay.
Please contact your doctor immediately if you develop an infection, the reaction to your shot worsens, or you experience any of the below symptoms, which may indicate a systemic allergic reaction:
- Difficulty breathing
- Widespread rash
- Facial swelling
Thrombotic events (blood clots that block your blood vessels) may occur after your PAPZIMEOS shot. Please notify your doctor immediately if you have the following symptoms:
- Shortness of breath
- Chest pain
- Leg swelling
- Persistent abdominal pain
- Severe or persistent headaches
- Blurred vision
What should I know before taking PAPZIMEOS?
Before taking PAPZIMEOS, tell your healthcare provider about all of your medical conditions, including:
- If you are pregnant or plan to become pregnant because it is not known if PAPZIMEOS will harm the unborn baby.
- If you are breastfeeding or plan to breastfeed. It is unknown if PAPZIMEOS is present in breast milk, or how it affects the breastfeeding child or milk production. Talk to your healthcare provider about the best way to feed your baby during treatment with PAPZIMEOS.
What are the most common side effects of PAPZIMEOS?
The most common side effects include:
- Pain, redness, or swelling where the shot was given
- Feeling tired
- Chills
- Fever
- Muscle aches
- Nausea (feeling sick)
- Headache
- Increased heart rate
- Diarrhea
- Vomiting
- Sweating a lot
These are not all of the possible side effects of PAPZIMEOS. Call your healthcare provider for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088. You may also report side effects to Precigen, Inc. at 1-855-PGE-NRRP (1-855-743-6777).
Please see full Prescribing Information.
What is PAPZIMEOS?
PAPZIMEOS is a type of immunotherapy used to treat a condition called recurrent respiratory papillomatosis (RRP) in adults.
Important Safety Information
What is the most important information I should know about PAPZIMEOS?
Some people may have a reaction to the shot. Signs and symptoms may include redness, pain, swelling, itching, or warmth where the shot was given. After your first treatment, your healthcare provider will watch you for at least 30 minutes to make sure you're feeling okay.